Retroviruses and the Placenta
نویسندگان
چکیده
منابع مشابه
Retroviruses and the Placenta
Retroviruses are often expressed in the placenta. Placental expression probably evolved to facilitate retroviral transmission from mother to offspring and from offspring to mother. In the process, the placenta became a site where retroviral genes were 'domesticated' to serve adaptive functions in the host, including the manipulation of maternal physiology for the benefit of the fetus. The evolu...
متن کاملRetroviruses and the Third Synapse
The direct movement of viruses between contacting cells as a mode of dissemination distinct from the release of cell-free virions was hinted at in pioneering experiments first reported almost eighty years ago [1], and confirmed and extended 30 years later [2,3]. This early work was carried out using the tools of the time in the absence of the modern cell biological, immunological and virologica...
متن کاملAberrant effect of genistein on placenta development expressed through alteration in transforming growth factor-β1 and alkaline phosphatase across the maternal serum, the placenta and the amniotic fluid
Objective(s): The mechanism via which genistein, the major isoflavone content of soya, adversely influenced placenta and fetal development was evaluated in pregnant laboratory rats.Materials and Methods: There were control, 2 mg/kg and 4 mg/kg genistein groups of rats with five sub-groups based on gestation termination day. At the end of...
متن کاملI-7: Maternal Signalling to the Placenta
Background: Though it is well established that maternal blood-borne signals influence highly the growth of the placenta, the mechanisms are not known. In vitro trophoblast culture models are limited by an inability to reconstruct the polarised bilayer of the human hemochorial placenta. We have used a first trimester villous tissue explant system to investigate how growth factors interact with p...
متن کامل[Retroviruses in the Caribbean].
Transmission of HIV in many Caribbean countries has followed the pattern of initial predominance among homosexual and bisexual males, with the infection subsequently spreading into the heterosexual community. However, on Saint Lucia the epidemic began among heterosexual contacts of Saint Lucian laborers from Florida; in Bermuda 58% of AIDS cases have been in intravenous drug abusers; and in the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2012
ISSN: 0960-9822
DOI: 10.1016/j.cub.2012.06.002